CPB2 抗体 (AA 166-388) (HRP)
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Quick Overview for CPB2 抗体 (AA 166-388) (HRP) (ABIN7974848)
抗原
See all CPB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 166-388
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原理
- Anti-Carboxypeptidase B2/CPB2 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1%,85.7% amino acid (aa) sequence identity with mouse,rat CPB2,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1% and 85.7% amino acid (aa) sequence identity with mouse and rat CPB2, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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别名
- CPB2
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背景
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Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
Gene Full Name: carboxypeptidase B2
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基因ID
- 1361
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UniProt
- Q96IY4
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途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
抗原
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