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Caldesmon 抗体 (AA 1-120) (HRP)

This 兔 多克隆 antibody specifically detects Caldesmon in WB, IHC 和 ELISA. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7974243
发货至: 中国
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Room 801-803
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Quick Overview for Caldesmon 抗体 (AA 1-120) (HRP) (ABIN7974243)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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  • 117
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人, 大鼠, 小鼠

宿主

  • 141
  • 34

克隆类型

  • 108
  • 67
多克隆

标记

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  • 1
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This Caldesmon antibody is conjugated to HRP

应用范围

  • 117
  • 78
  • 33
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  • 27
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  • 21
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 23
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    AA 1-120

    原理

    Anti-Caldesmon/CALD1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    coli-derived human Caldesmon recombinant protein (Position: M1-E120). Human Caldesmon shares 87.6% amino acid (aa) sequence identity with rat Caldesmon.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Caldesmon recombinant protein (Position: M1-E120). Human Caldesmon shares 87.6% amino acid (aa) sequence identity with rat Caldesmon.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    CALD1

    背景

    Background: Caldesmon is a protein that in humans is encoded by the CALD1 gene. It is mapped to 7q33. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

    Gene Full Name: caldesmon 1

    基因ID

    800

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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