CAMLG 抗体 (Middle Region) (HRP)
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北京 101111
Quick Overview for CAMLG 抗体 (Middle Region) (HRP) (ABIN7974122)
抗原
See all CAMLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-CAMLG Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CAMLG shares 91.7%,95.7% amino acid (aa) sequence identity with mouse,rat CAMLG,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human CAMLG. Human CAMLG shares 91.7% and 95.7% amino acid (aa) sequence identity with mouse and rat CAMLG, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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别名
- CAMLG
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背景
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Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Gene Full Name: calcium modulating ligand
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基因ID
- 819
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UniProt
- P49069
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途径
- EGFR Signaling Pathway
抗原
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