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BUB1 抗体 (AA 26-1085) (FITC)

The FITC-conjugated 兔 多克隆 anti-BUB1 antibody (ABIN7973438) specifically detects BUB1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7973438
发货至: 中国
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Quick Overview for BUB1 抗体 (AA 26-1085) (FITC) (ABIN7973438)

抗原

See all BUB1 抗体
BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

适用

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  • 60
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  • 1
人, 小鼠, 大鼠

宿主

  • 112
  • 8
兔

克隆类型

  • 101
  • 19
多克隆

标记

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  • 1
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This BUB1 antibody is conjugated to FITC

应用范围

  • 101
  • 56
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  • 10
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 26-1085

    原理

    Anti-BUB1 Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BUB1 recombinant protein (Position: E26-K1085).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

    说明

    Applications are recommended based on the unconjugated antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

    别名

    BUB1

    背景

    Background: BUB1, also known as mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It is mapped to 2q13. BUB1 is first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.

    Gene Full Name: BUB1 mitotic checkpoint serine/threonine kinase

    基因ID

    699

    UniProt

    O43683
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