BUB1 抗体 (AA 731-1085)
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北京 101111
Quick Overview for BUB1 抗体 (AA 731-1085) (ABIN7973421)
抗原
See all BUB1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 731-1085
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原理
- Anti-Bub1 AAMP Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.
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产品特性
- Anti-Bub1 AAMP Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Bub1 recombinant protein (Position: V731-K1085). Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.
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亚型
- IgG
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anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-130) antibody
BUB1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-1085) antibodyBUB1 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-1085) antibodyBUB1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C3-4C9 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-130) antibodyBUB1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A11C7 unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-300) antibodyBUB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) antibodyKD Validated BUB1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3065 unconjugated Recombinant Antibody
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 951-1085) antibodyBUB1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 26-1085) antibodyBUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-1085) antibodyBUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1-30), (N-Term) antibodyBUB1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB15014 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
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别名
- BUB1
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背景
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Background: BUB1, also known as mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It is mapped to 2q13. BUB1 is first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.
Gene Full Name: BUB1 mitotic checkpoint serine/threonine kinase
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. BUB1 subfamily.
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分子量
- 130 kDa
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基因ID
- 699
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UniProt
- O43683
抗原
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