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BUB1 抗体 (AA 731-1085) (APC)

This 兔 多克隆 antibody specifically detects BUB1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7973418
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BUB1 抗体 (AA 731-1085) (APC) (ABIN7973418)

抗原

See all BUB1 抗体
BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

适用

  • 104
  • 74
  • 52
  • 1
人, 小鼠, 大鼠

宿主

  • 110
  • 8

克隆类型

  • 99
  • 19
多克隆

标记

  • 51
  • 7
  • 7
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BUB1 antibody is conjugated to APC

应用范围

  • 78
  • 44
  • 35
  • 32
  • 13
  • 13
  • 13
  • 10
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 731-1085

    原理

    Anti-Bub1 AAMP Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Bub1 recombinant protein (Position: V731-K1085). Human Bub1 shares 81% amino acid (aa) sequence identity with mouse Bub1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))

    别名

    BUB1

    背景

    Background: BUB1, also known as mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It is mapped to 2q13. BUB1 is first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of BUB1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. The protein kinase BUB1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.

    Gene Full Name: BUB1 mitotic checkpoint serine/threonine kinase

    Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. BUB1 subfamily.

    基因ID

    699

    UniProt

    O43683
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