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BIN1 抗体 (AA 45-593) (Fluoro594)

The 兔 多克隆 anti-BIN1 antibody is suitable to detect BIN1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7973272
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for BIN1 抗体 (AA 45-593) (Fluoro594) (ABIN7973272)

抗原

See all BIN1 抗体
BIN1 (Bridging Integrator 1 (BIN1))

适用

  • 88
  • 51
  • 33
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 72
  • 17
  • 1

克隆类型

  • 46
  • 44
多克隆

标记

  • 54
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIN1 antibody is conjugated to Fluoro594

应用范围

  • 69
  • 48
  • 36
  • 31
  • 30
  • 23
  • 23
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 45-593

    原理

    Anti-BIN1 Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BIN1 recombinant protein (Position: E45-P593).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BIN1 (Bridging Integrator 1 (BIN1))

    别名

    BIN1

    背景

    Background: Myc box-dependent-interacting protein 1, also known as Bridging Integrator-1 and Amphiphysin-2 is a protein that in humans is encoded by the BIN1 gene. This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

    Gene Full Name: bridging integrator 1

    基因ID

    274

    UniProt

    O00499
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