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BCCIP 抗体 (AA 167-300) (Cy3)

The 兔 多克隆 anti-BCCIP antibody is suitable to detect BCCIP in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7973170
发货至: 中国
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Quick Overview for BCCIP 抗体 (AA 167-300) (Cy3) (ABIN7973170)

抗原

See all BCCIP 抗体
BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

适用

人, 小鼠, 大鼠

宿主

  • 44
  • 5

克隆类型

  • 48
  • 1
多克隆

标记

  • 25
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCCIP antibody is conjugated to Cy3

应用范围

  • 21
  • 14
  • 13
  • 13
  • 13
  • 11
  • 11
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-300

    原理

    Anti-BCCIP Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BCCIP recombinant protein (Position: K167-K300).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))

    别名

    BCCIP

    背景

    Background: BRCA2 and CDKN1A-interacting protein is a protein that in humans is encoded by the BCCIP gene. This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.

    Gene Full Name: BRCA2 and CDKN1A interacting protein

    基因ID

    56647

    UniProt

    Q9P287
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