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beta-2 Microglobulin 抗体 (AA 21-119) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-beta-2 Microglobulin antibody (ABIN7972619) specifically detects beta-2 Microglobulin in WB, IHC 和 ELISA. The antibody is reactive with 小鼠 和 大鼠 samples.
产品编号 ABIN7972619
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for beta-2 Microglobulin 抗体 (AA 21-119) (Biotin) (ABIN7972619)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta-2 Microglobulin antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 21-119

    原理

    Anti-beta 2 Microglobulin/B2m Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat beta 2 Microglobulin/B2m recombinant protein (Position: I21-M119).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    B2m

    背景

    Background: Beta-2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the beta-2-microglobulin protein is encoded by the B2M gene. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

    Gene Full Name: beta-2 microglobulin

    基因ID

    12010

    UniProt

    P01887

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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