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Bestrophin 1 抗体 (AA 9-551) (PE)

This 兔 多克隆 antibody specifically detects Bestrophin 1 in FACS. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN7972605
发货至: 中国
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Quick Overview for Bestrophin 1 抗体 (AA 9-551) (PE) (ABIN7972605)

抗原

See all Bestrophin 1 (BEST1) 抗体
Bestrophin 1 (BEST1)

适用

  • 36
  • 17
  • 16
  • 2
  • 2
  • 1
小鼠, 大鼠

宿主

  • 45
  • 4

克隆类型

  • 47
  • 2
多克隆

标记

  • 22
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Bestrophin 1 antibody is conjugated to PE

应用范围

  • 27
  • 17
  • 14
  • 10
  • 4
  • 2
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 9-551

    原理

    Anti-Bestrophin-1/Best1 Antibody PE Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Bestrophin-1/Best1 recombinant protein (Position: V9-E551). Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Bestrophin 1 (BEST1)

    别名

    Best1

    背景

    Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

    Gene Full Name: bestrophin 1

    基因ID

    24115

    UniProt

    O88870
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