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BAG3 抗体 (AA 100-561)

This 兔 多克隆 antibody specifically detects BAG3 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7972353
发货至: 中国
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北京 101111
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Quick Overview for BAG3 抗体 (AA 100-561) (ABIN7972353)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAG3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

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    AA 100-561

    原理

    Anti-Bag3 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human Bag3 shares 84.1% amino acid (aa) sequence identity with mouse Bag3.

    产品特性

    Anti-Bag3 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Bag3 recombinant protein (Position: H100-N561). Human Bag3 shares 84.1% amino acid (aa) sequence identity with mouse Bag3.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    BAG3

    背景

    Background: BAG family molecular chaperone regulator 3 (BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies, mice and men.

    Gene Full Name: BAG cochaperone 3

    分子量

    80 kDa

    基因ID

    9531

    UniProt

    O95817
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