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BAG3 抗体 (AA 100-561) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-BAG3 antibody (ABIN7972346) specifically detects BAG3 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7972346
发货至: 中国
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Quick Overview for BAG3 抗体 (AA 100-561) (Fluoro550) (ABIN7972346)

抗原

See all BAG3 抗体
BAG3 (BCL2-Associated Athanogene 3 (BAG3))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAG3 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 100-561

    原理

    Anti-Bag3 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human Bag3 shares 84.1% amino acid (aa) sequence identity with mouse Bag3.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Bag3 recombinant protein (Position: H100-N561). Human Bag3 shares 84.1% amino acid (aa) sequence identity with mouse Bag3.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BAG3 (BCL2-Associated Athanogene 3 (BAG3))

    别名

    BAG3

    背景

    Background: BAG family molecular chaperone regulator 3 (BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies, mice and men.

    Gene Full Name: BAG cochaperone 3

    基因ID

    9531

    UniProt

    O95817
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