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BAG2 抗体 (AA 1-211) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-BAG2 antibody (ABIN7972310) specifically detects BAG2 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7972310
发货至: 中国
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Quick Overview for BAG2 抗体 (AA 1-211) (Biotin) (ABIN7972310)

抗原

See all BAG2 抗体
BAG2 (BCL2-Associated Athanogene 2 (BAG2))

适用

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宿主

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克隆类型

  • 75
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多克隆

标记

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This BAG2 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 30
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    AA 1-211

    原理

    Anti-BAG2 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    BAG2 (BCL2-Associated Athanogene 2 (BAG2))

    别名

    BAG2

    背景

    Background: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

    Gene Full Name: BAG cochaperone 2

    Sequence Similarities: Contains 1 P-type (trefoil) domain.

    基因ID

    9532

    UniProt

    O95816
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