B-Cell Linker 抗体 (AA 59-456) (FITC)
Our Local Distributor
北京 101111
Quick Overview for B-Cell Linker 抗体 (AA 59-456) (FITC) (ABIN7971939)
抗原
See all B-Cell Linker (BLNK) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 59-456
-
原理
- Anti-BLNK Antibody FITC Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human BLNK recombinant protein (Position: D59-S456).
-
亚型
- IgG
-
-
anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-B-Cell Linker (BLNK) (AA 65-314) antibodyBLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 301-400) antibodyBLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-B-Cell Linker (BLNK) (C-Term) antibodyVerified BLNK 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 150-178) antibodyBLNK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18883 unconjugated
anti-B-Cell Linker (BLNK) (AA 41-337) antibodyBLNK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 1-456) antibodyBLNK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr84) antibodyBLNK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- B-Cell Linker (BLNK)
-
别名
- BLNK
-
背景
-
Background: The B-cell linker protein is encoded by the BLNK gene and is an adaptor protein also known as SLP-65, BASH, and BCA. This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
Gene Full Name: B cell linker
-
基因ID
- 29760
-
UniProt
- Q8WV28
-
途径
- BCR Signaling
抗原
-
