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BCL6 抗体 (AA 28-336) (HRP)

This 兔 多克隆 antibody specifically detects BCL6 in IHC, WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7971918
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BCL6 抗体 (AA 28-336) (HRP) (ABIN7971918)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCL6 antibody is conjugated to HRP

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

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    AA 28-336

    原理

    Anti-BCL6 Antibody HRP Conjugated

    预测反应

    Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BCL6 recombinant protein (Position: R28-K336). Human BCL6 shares 90.6% amino acid (aa) sequence identity with mouse BCL6.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL6

    背景

    Background: Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    Gene Full Name: BCL6 transcription repressor

    基因ID

    604

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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