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BCL6 抗体 (N-Term)

The 兔 多克隆 anti-BCL6 antibody (ABIN7971911) specifically detects BCL6 in IHC, WB, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7971911
发货至: 中国
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Room 801-803
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Quick Overview for BCL6 抗体 (N-Term) (ABIN7971911)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

Carrier-free
  • 抗原表位

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    N-Term

    原理

    Anti-BCL6 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    产品特性

    Anti-BCL6 Antibody. Tested in ICC/IF, IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human BCL6, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL6

    背景

    Background: B-cell lymphoma 6 protein is a protein that in humans is encoded by the BCL6 gene. Like BCL2, BCL3, BCL5, BCL7A, BCL9 and BCL10, it has clinical significance in lymphoma. The protein encoded by this gene is an evolutionarily conserved zinc finger transcription factor and contains an N-terminal POZ/BTB domain. This protein acts as a sequence-specific repressor of transcription and has been shown to modulate the STAT-dependent Interleukin 4 (IL-4) responses of B cells. This protein can interact with several corepressor complexes to inhibit transcription. This gene is found to be frequently translocated and hypermutated in diffuse large B cell lymphoma (DLBCL) and contributes to the pathogenesis of DLBCL. An exon 7 skipping splice variant encodes a shorter form of the protein which lacks the first two zinc fingers of the DNA binding domain.

    Gene Full Name: BCL6 transcription repressor

    分子量

    90-95 kDa

    基因ID

    604

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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