AIRE 抗体 (AA 1-120) (Cy3)
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Quick Overview for AIRE 抗体 (AA 1-120) (Cy3) (ABIN7971593)
抗原
See all AIRE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-120
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原理
- Anti-AIRE Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human AIRE shares 87.2% amino acid (aa) sequence identity with mouse AIRE.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AIRE recombinant protein (Position: M1-K120). Human AIRE shares 87.2% amino acid (aa) sequence identity with mouse AIRE.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- AIRE (Autoimmune Regulator (AIRE))
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别名
- AIRE
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背景
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Background: The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Gene Full Name: autoimmune regulator
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基因ID
- 326
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UniProt
- O43918
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途径
- Chromatin Binding
抗原
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