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ATR 抗体 (AA 24-1324) (Fluoro488)

This 兔 多克隆 antibody specifically detects ATR in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7971495
发货至: 中国
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Quick Overview for ATR 抗体 (AA 24-1324) (Fluoro488) (ABIN7971495)

抗原

See all ATR 抗体
ATR (ATR serine/threonine kinase (ATR))

适用

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宿主

  • 65
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克隆类型

  • 68
  • 5
多克隆

标记

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This ATR antibody is conjugated to Fluoro488

应用范围

  • 37
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Flow Cytometry (FACS)
  • 抗原表位

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    AA 24-1324

    原理

    Anti-ATR Antibody Fluoro488 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATR recombinant protein (Position: E24-D1324).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ATR (ATR serine/threonine kinase (ATR))

    别名

    ATR

    背景

    Background: Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene. The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

    Gene Full Name: ATR checkpoint kinase

    基因ID

    545

    UniProt

    Q13535

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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