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Id2 抗体 (AA 31-134)

This anti-Id2 antibody is a 兔 多克隆 antibody detecting Id2 in ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN747473
发货至: 中国

Quick Overview for Id2 抗体 (AA 31-134) (ABIN747473)

抗原

See all Id2 抗体
Id2 (Inhibitor of DNA Binding 2 (Id2))

适用

  • 35
  • 31
  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
大鼠

宿主

  • 40
  • 9
  • 1

克隆类型

  • 42
  • 8
多克隆

标记

  • 23
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Id2 antibody is un-conjugated

应用范围

  • 22
  • 19
  • 12
  • 12
  • 9
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-134

    特异性

    Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GIG8/ID2

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Id2 (Inhibitor of DNA Binding 2 (Id2))

    别名

    ID2

    背景

    Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2

    Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    基因ID

    3398

    UniProt

    Q02363
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