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ATP2A3 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects ATP2A3 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7971294
发货至: 中国
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Quick Overview for ATP2A3 抗体 (N-Term) (ABIN7971294)

抗原

See all ATP2A3 抗体
ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

适用

  • 41
  • 17
  • 16
  • 15
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 41
  • 2

克隆类型

  • 41
  • 2
多克隆

标记

  • 13
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATP2A3 antibody is un-conjugated

应用范围

  • 29
  • 13
  • 13
  • 8
  • 8
  • 8
  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-SERCA3 ATPase/ATP2A3 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by five amino acids,and from the related rat sequence by six amino acids.

    产品特性

    Anti-SERCA3 ATPase/ATP2A3 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human ATP2A3, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, HumanWestern blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

    别名

    ATP2A3

    背景

    Background: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, also known as SERCA3, is anenzyme that in humans is encoded by the ATP2A3 gene. It is mapped to 17p13.2. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of cells. ATP2A3 expression was originally described as non-muscular, but was recently observed in cardiomyocyte. What's more, the expression of ATP2A3 was significantly reduced or lost in colon carcinomas compared with normal colonic epithelial cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.

    Gene Full Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

    Sequence Similarities: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.

    分子量

    114 kDa

    基因ID

    489

    UniProt

    Q93084

    途径

    Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process
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