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ABCG1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects ABCG1 in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7971096
发货至: 中国
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Quick Overview for ABCG1 抗体 (C-Term) (ABIN7971096)

抗原

See all ABCG1 抗体
ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))

适用

  • 87
  • 49
  • 38
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 84
  • 3
  • 1

克隆类型

  • 64
  • 24
多克隆

标记

  • 28
  • 10
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ABCG1 antibody is un-conjugated

应用范围

  • 59
  • 29
  • 26
  • 20
  • 17
  • 14
  • 13
  • 13
  • 7
  • 3
  • 3
  • 2
Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 16
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-ABCG1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    产品特性

    Anti-ABCG1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ABCG1, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))

    别名

    ABCG1

    背景

    Background: ABCG1 (Atp-binding cassette, subfamily g, member 1) also known as ABC8, ABC TRANSPORTER 8 or WHITE, DROSOPHILA, HOMOLOG OF, is a protein that in humans is encoded by the ABCG1 gene. ABCG1 is a regulator of macrophage cholesterol and phospholipid transport. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.The ABCG1 gene is mapped on 21q22.3. This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. ABCG1 is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. Inhibition of ABCG1 protein expression using an antisense strategy resulted in reduced HDL3-dependent efflux of cholesterol and choline-phospholipids. In macrophages, silencing of GPS2 by RNA interference reduced ABCG1 expression and diminished ABCG1-mediated cholesterol efflux.

    Gene Full Name: ATP binding cassette subfamily G member 1

    Sequence Similarities: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.

    分子量

    75 kDa

    基因ID

    9619

    UniProt

    P45844

    途径

    Lipid Metabolism
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