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Aspartate beta Hydroxylase 抗体 (C-Term) (FITC)

The 兔 多克隆 anti-Aspartate beta Hydroxylase antibody is suitable to detect Aspartate beta Hydroxylase in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7970395
发货至: 中国
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Quick Overview for Aspartate beta Hydroxylase 抗体 (C-Term) (FITC) (ABIN7970395)

抗原

See all Aspartate beta Hydroxylase (ASPH) 抗体
Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Aspartate beta Hydroxylase antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-Aspartate beta hydroxylase/ASPH Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ASPH, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

    别名

    ASPH

    背景

    Background: ASPH is also known as Aspartyl/asparaginyl beta-hydroxylase. This gene is thought to play an important role in calcium homeostasis. And the gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

    Gene Full Name: aspartate beta-hydroxylase

    Sequence Similarities: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

    基因ID

    444

    UniProt

    Q12797

    途径

    Positive Regulation of Endopeptidase Activity
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