ARNTL 抗体 (AA 116-447) (PE)
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Quick Overview for ARNTL 抗体 (AA 116-447) (PE) (ABIN7970288)
抗原
See all ARNTL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 116-447
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原理
- Anti-BMAL1/ARNTL Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BMAL1/ARNTL recombinant protein (Position: R116-E447).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
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别名
- ARNTL
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背景
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Background: Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: basic helix-loop-helix ARNT like 1
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基因ID
- 406
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UniProt
- O00327
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途径
- Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
抗原
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