Aryl Hydrocarbon Receptor 抗体 (Middle Region) (Cy3)
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Quick Overview for Aryl Hydrocarbon Receptor 抗体 (Middle Region) (Cy3) (ABIN7970182)
抗原
See all Aryl Hydrocarbon Receptor (AHR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Aryl hydrocarbon Receptor/AHR Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related human sequence by five amino acids,and from the related rat sequence by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse AHR, different from the related human sequence by five amino acids, and from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibody
AHR 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (C-Term) antibodyAHR 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (pSer36) antibodyAHR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) antibodyKD Validated AHR 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1635 unconjugated Recombinant Antibody
anti-Aryl Hydrocarbon Receptor (AHR) (AA 555-582) antibodyAHR 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 128-399) antibodyAHR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (Internal Region) antibodyVerified AHR 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibodyAHR 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G7 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (AA 721-820) antibodyAHR 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5E6A9 unconjugated
anti-Aryl Hydrocarbon Receptor (AHR) (N-Term) antibodyAHR 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Aryl Hydrocarbon Receptor (AHR)
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别名
- Ahr
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背景
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Background: AHR (aryl hydrocarbon receptor), also called bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The AHR gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr -/- or Er-alpha -/- ovariectomized mice. Complex assembly and ubiquitin ligase activity of CUL4B (AHR) in vitro and in vivo are dependent on the AHR ligand. In the CUL4B (AHR) complex, ligand-activated AHR acts as a substrate-specific adaptor component that targets sex steroid receptors for degradation. Cd4-positive cells from mice lacking Ahr developed Th17 responses but failed to produce Il22 and did not show enhanced Th17 development. Activation of Ahr during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in Ahr -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Ahr activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.
Gene Full Name: aryl-hydrocarbon receptor
Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.
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基因ID
- 11622
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UniProt
- P30561
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途径
- Regulation of Cell Size
抗原
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