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Arrestin 3 抗体 (C-Term) (Fluoro488)

The 兔 多克隆 anti-Arrestin 3 antibody is suitable to detect Arrestin 3 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7970161
发货至: 中国
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Quick Overview for Arrestin 3 抗体 (C-Term) (Fluoro488) (ABIN7970161)

抗原

See all Arrestin 3 (ARRB2) 抗体
Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

适用

  • 68
  • 42
  • 42
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 8
  • 5

克隆类型

  • 60
  • 8
多克隆

标记

  • 30
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Arrestin 3 antibody is conjugated to Fluoro488

应用范围

  • 46
  • 21
  • 20
  • 14
  • 13
  • 13
  • 13
  • 12
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Beta Arrestin 2/ARRB2 Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Beta Arrestin 2, different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

    别名

    ARRB2

    背景

    Background: ARRB2 (arrestin beta-2), also known as Beta-arrestin-2, BARR2, ARB2, DKFZp686L0365, arrestin 3, is an intracellularprotein that in humans is encoded by the ARRB2 gene. Members of arrestin/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Beta-arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors.

    Gene Full Name: arrestin beta 2

    Sequence Similarities: Belongs to the arrestin family.

    基因ID

    409

    UniProt

    P32121

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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