AANAT 抗体 (AA 24-205) (Fluoro488)
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Quick Overview for AANAT 抗体 (AA 24-205) (Fluoro488) (ABIN7969886)
抗原
See all AANAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-205
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原理
- Anti-Aanat Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Aanat recombinant protein (Position: C24-C205).
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亚型
- IgG
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anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 141-207) antibody
AANAT 适用: 人, 小鼠, 大鼠, 绵羊 ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 22-235) antibodyAANAT 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 1-207) antibodyAANAT 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 27-54), (N-Term) antibodyAANAT 适用: 人 WB 宿主: 兔 Polyclonal RB23834 unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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别名
- Aanat
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背景
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Background: Aralkylamine N-acetyltransferase (AANAT) (EC 2.3.1.87), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin. It is in humans encoded by the ~2.5 kb AANAT gene containing four exons, located on chromosome 17q25. The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternative splicing results in multiple transcript variants.
Gene Full Name: arylalkylamine N-acetyltransferase
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基因ID
- 11298
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UniProt
- O88816
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途径
- Photoperiodism
抗原
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