ALOX15 抗体 (AA 2-337) (PE)
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Quick Overview for ALOX15 抗体 (AA 2-337) (PE) (ABIN7969848)
抗原
See all ALOX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-337
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原理
- Anti-15 Lipoxygenase 1/ALOX15 Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human ALOX15 shares 72%,73% amino acid (aa) sequences identity with mouse,rat ALOX15,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
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别名
- ALOX15
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背景
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Background: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in ionally opposite manners.
Gene Full Name: arachidonate 15-lipoxygenase
Sequence Similarities: Belongs to the lipoxygenase family.
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基因ID
- 246
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UniProt
- P16050
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途径
- Regulation of Actin Filament Polymerization
抗原
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