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ALOX15 抗体 (AA 2-337) (Biotin)

The 兔 多克隆 anti-ALOX15 antibody is suitable to detect ALOX15 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7969840
发货至: 中国
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Quick Overview for ALOX15 抗体 (AA 2-337) (Biotin) (ABIN7969840)

抗原

See all ALOX15 抗体
ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ALOX15 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 2-337

    原理

    Anti-15 Lipoxygenase 1/ALOX15 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human ALOX15 shares 72%,73% amino acid (aa) sequences identity with mouse,rat ALOX15,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

    别名

    ALOX15

    背景

    Background: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in ionally opposite manners.

    Gene Full Name: arachidonate 15-lipoxygenase

    Sequence Similarities: Belongs to the lipoxygenase family.

    基因ID

    246

    UniProt

    P16050

    途径

    Regulation of Actin Filament Polymerization
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