ALOX12 抗体 (AA 186-628) (HRP)
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北京 101111
Quick Overview for ALOX12 抗体 (AA 186-628) (HRP) (ABIN7969835)
抗原
See all ALOX12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 186-628
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原理
- Anti-ALOX12 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human ALOX12 shares 87.3%,86% amino acid (aa) sequence identity with mouse,rat ALOX12,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALOX12 recombinant protein (Position: A186-R628). Human ALOX12 shares 87.3% and 86% amino acid (aa) sequence identity with mouse and rat ALOX12, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
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别名
- ALOX12
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背景
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Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNA Arachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
Gene Full Name: arachidonate 12-lipoxygenase, 12S type
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基因ID
- 239
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UniProt
- P18054
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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