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Aquaporin 4 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects Aquaporin 4 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7969740
发货至: 中国
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Quick Overview for Aquaporin 4 抗体 (C-Term) (ABIN7969740)

抗原

See all Aquaporin 4 (AQP4) 抗体
Aquaporin 4 (AQP4)

适用

  • 139
  • 113
  • 101
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 130
  • 39
  • 1
  • 1

克隆类型

  • 118
  • 52
  • 1
多克隆

标记

  • 80
  • 18
  • 8
  • 7
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aquaporin 4 antibody is un-conjugated

应用范围

  • 99
  • 84
  • 51
  • 38
  • 29
  • 24
  • 20
  • 16
  • 13
  • 13
  • 6
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 47
    • 16
    • 16
    • 13
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Aquaporin 4/AQP4 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related rat,mouse sequences by two amino acids.

    产品特性

    Anti-Aquaporin 4/AQP4 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4, different from the related rat and mouse sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Aquaporin 4 (AQP4)

    别名

    AQP4

    背景

    Background: AQP4 (Aquaporin 4), also known as MERCURIAL-INSENSITIVE WATER CHANNEL, MIWC, is protein which in humans is encoded by the AQP4 gene. The aquaporins are a family of water-selective membrane channels found in animals, plants, and microorganisms. AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. By fluorescence in situ hybridization, Lu et al. (1996) determined that the AQP4 gene maps to 18q11.2-q12.1. By interspecific backcross analysis, Turtzo et al. (1997) mapped the mouse Aqp4 gene to the proximal region of chromosome 18. Analyzing the expression of AQP4 in mammalian skeletal muscle, Frigeri et al. (1998) found that, in immunohistochemical experiments, affinity-purified AQP4 antibodies stained selectively the sarcolemma of fast-twitch fibers. Immunocytochemistry revealed strong AQP4 water channel expression in Muller cells in mouse retina and in fibrous astrocytes in optic nerve.

    Gene Full Name: aquaporin 4

    Sequence Similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family.

    分子量

    24 kDa

    基因ID

    361

    UniProt

    P55087

    途径

    Sensory Perception of Sound
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