APOE 抗体 (AA 55-294) (Fluoro488)
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Quick Overview for APOE 抗体 (AA 55-294) (Fluoro488) (ABIN7969446)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-294
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原理
- Anti-Apolipoprotein E/APOE Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Mouse Apolipoprotein E shares 75%,94.6% amino acid (aa) sequence identity with human,rat Apolipoprotein E,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- APOE (Apolipoprotein E (APOE))
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别名
- Apoe
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背景
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Background: APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.
Gene Full Name: apolipoprotein E
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基因ID
- 11816
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UniProt
- P08226
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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