AMH 抗体 (AA 75-141) (Fluoro594)
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Quick Overview for AMH 抗体 (AA 75-141) (Fluoro594) (ABIN7969129)
抗原
See all AMH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-141
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原理
- Anti-AMH Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- Human AMH shares 66.7% amino acid (aa) sequence identity with both mouse,rat AMH.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human AMH recombinant protein (Position: A75-E141). Human AMH shares 66.7% amino acid (aa) sequence identity with both mouse and rat AMH.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- AMH (Anti-Mullerian Hormone (AMH))
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别名
- AMH
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背景
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Background: Anti-Müllerian hormone (AMH), also known as MIF or MIS, is a protein that in humans is encoded by the AMH gene. It is a hormone that inhibits the development of the Müllerian ducts (paramesonephric ducts) in the male embryo. Expression of AMH is activated by SOX9 in the male Sertoli cells and causes the irreversible regression of the Müllerian ducts. Because AMH expression is critical to sex differentiation at a specific time during fetal development, it appears to be tightly regulated by SF1, GATA factors, DAX1 and FSH. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.
Gene Full Name: anti-Mullerian hormone
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基因ID
- 268
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UniProt
- P03971
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途径
- Negative Regulation of Hormone Secretion
抗原
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