ANTXR1 抗体 (AA 33-301)
Our Local Distributor
北京 101111
Quick Overview for ANTXR1 抗体 (AA 33-301) (ABIN7969124)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 33-301
-
原理
- Anti-TEM8/ATR/ANTXR1 Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-TEM8/ATR/ANTXR1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human TEM8/ATR/ANTXR1 recombinant protein (Position: E33-D301).
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
-
别名
- ANTXR1
-
背景
-
Background: Anthrax toxin receptor 1 (ANTXR1 or also known asTEM8) is a protein that in humans is encoded by the ANTXR1 gene. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Gene Full Name: ANTXR cell adhesion molecule 1
-
分子量
- 80 kDa
-
基因ID
- 84168
-
UniProt
- Q9H6X2
抗原
-