Annexin a1 抗体 (AA 2-346) (HRP)
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北京 101111
Quick Overview for Annexin a1 抗体 (AA 2-346) (HRP) (ABIN7968834)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-346
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原理
- Anti-Annexin A1/ANXA1 Antibody (monoclonal, 6B7F8) HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- Human Annexin A1 shares 88%,89% amino acid (aa) sequence identity with mouse,rat Annexin A1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Annexin A1 recombinant protein (Position: A2-N346). Human Annexin A1 shares 88% and 89% amino acid (aa) sequence identity with mouse and rat Annexin A1, respectively.
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亚型
- IgG2b
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anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated
anti-Annexin A1 (ANXA1) (AA 144-248) antibodyANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Annexin A1 (ANXA1) antibodyKD Validated ANXA1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB6815 unconjugated Recombinant Antibody
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 2-346) antibodyANXA1 适用: 人, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (C-Term) antibodyVerified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- ANXA1
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背景
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Background: ANXA1, also known as lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. ANXA1 belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.
Gene Full Name: annexin A1
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基因ID
- 301
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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