Erythrocyte Ankyrin 抗体 (AA 1300-1844) (Fluoro488)
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Quick Overview for Erythrocyte Ankyrin 抗体 (AA 1300-1844) (Fluoro488) (ABIN7968786)
抗原
See all Erythrocyte Ankyrin (ANK1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1300-1844
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原理
- Anti-Ankyrin erythroid/ANK/ANK1 Antibody (monoclonal, 5H2E8) Fluoro488 Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Ankyrin erythroid/ANK/ANK1 recombinant protein (Position: N1300-Q1844).
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亚型
- IgG2a
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anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1300-1844) antibody
ANK1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin 1, Erythrocytic (ANK1) (C-Term) antibodyANK1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 390)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 390
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 488)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 488
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 594)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 594
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Biotin)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Biotin
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (FITC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 FITC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (APC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 APC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PerCP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PerCP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PE)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PE
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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别名
- ANK1
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背景
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Background: Ankyrin 1, erythrocytic, also known as ANK1, is a protein that in humans is encoded by the ANK1 gene. Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats, a central region with a highly conserved spectrin binding domain, and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.
Gene Full Name: ankyrin 1
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基因ID
- 286
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UniProt
- P16157
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途径
- Synaptic Membrane
抗原
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