Ancient Ubiquitous Protein 1 抗体 (AA 77-399) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for Ancient Ubiquitous Protein 1 抗体 (AA 77-399) (Cy3) (ABIN7968389)
抗原
See all Ancient Ubiquitous Protein 1 (Aup1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 77-399
-
原理
- Anti-AUP1 Antibody Cy3 Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human AUP1 recombinant protein (Position: A77-R399).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- Ancient Ubiquitous Protein 1 (Aup1)
-
别名
- AUP1
-
背景
-
Background: Ancient ubiquitous protein 1 is a protein that in humans is encoded by the AUP1 gene. The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.
Gene Full Name: AUP1 lipid droplet regulating VLDL assembly factor
-
基因ID
- 550
-
UniProt
- Q9Y679
抗原
-