APCS 抗体 (AA 21-228) (Fluoro488)
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Quick Overview for APCS 抗体 (AA 21-228) (Fluoro488) (ABIN7968335)
抗原
See all APCS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-228
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原理
- Anti-Serum Amyloid P/APCS Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Rat Serum Amyloid P shares 72%,80% amino acid (aa) sequences identity with human,mouse Serum Amyloid P,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived rat Serum Amyloid P recombinant protein (Position: Q21-S228). Rat Serum Amyloid P shares 72% and 80% amino acid (aa) sequences identity with human and mouse Serum Amyloid P, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- APCS (Amyloid P Component, Serum (APCS))
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别名
- APCS
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背景
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Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called amyloid. It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Gene Full Name: amyloid P component, serum
Sequence Similarities: Belongs to the pentaxin family.
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基因ID
- 29339
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UniProt
- P23680
抗原
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