alpha Fetoprotein 抗体 (AA 378-609) (Fluoro488)
Our Local Distributor
北京 101111
Quick Overview for alpha Fetoprotein 抗体 (AA 378-609) (Fluoro488) (ABIN7967917)
抗原
See all alpha Fetoprotein (AFP) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 378-609
-
原理
- Anti-alpha 1 Fetoprotein/AFP Antibody Fluoro488 Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human AFP shares 71%,73% amino acid (aa) sequences identity with mouse,rat AFP,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
-
别名
- AFP
-
背景
-
Background: AFP, also called Alpha-fetoprotein, alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.
Gene Full Name: alpha fetoprotein
Sequence Similarities: Belongs to the ALB/AFP/VDB family.
-
基因ID
- 174
-
UniProt
- P02771
-
途径
- C21-Steroid Hormone Metabolic Process
抗原
-