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P5CS 抗体 (AA 1-224) (PE)

This 兔 多克隆 antibody specifically detects P5CS in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7967461
发货至: 中国
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Quick Overview for P5CS 抗体 (AA 1-224) (PE) (ABIN7967461)

抗原

See all P5CS (ALDH18A1) 抗体
P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

适用

  • 34
  • 18
  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 31
  • 4
  • 1

克隆类型

  • 34
  • 2
多克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This P5CS antibody is conjugated to PE

应用范围

  • 27
  • 18
  • 8
  • 4
  • 3
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-224

    原理

    Anti-P5CS/ALDH18A1 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human P5CS/ALDH18A1 recombinant protein (Position: M1-A224).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

    别名

    ALDH18A1

    背景

    Background: Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

    Gene Full Name: aldehyde dehydrogenase 18 family member A1

    基因ID

    5832

    UniProt

    P54886
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