P5CS 抗体 (AA 1-224) (HRP)
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北京 101111
Quick Overview for P5CS 抗体 (AA 1-224) (HRP) (ABIN7967459)
抗原
See all P5CS (ALDH18A1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-224
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原理
- Anti-P5CS/ALDH18A1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human P5CS/ALDH18A1 recombinant protein (Position: M1-A224).
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亚型
- IgG
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anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibody
ALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 176-205) antibodyALDH18A1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21608 unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 575-625) antibodyALDH18A1 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 696-795) antibodyALDH18A1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-795) antibodyALDH18A1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 745-795) antibodyALDH18A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 35-84) antibodyALDH18A1 适用: 人, 小鼠, 大鼠, Cow, Pig, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (N-Term) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1) (AA 1-240) antibodyALDH18A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
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别名
- ALDH18A1
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背景
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Background: Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is mapped to 10q24.1. This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
Gene Full Name: aldehyde dehydrogenase 18 family member A1
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基因ID
- 5832
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UniProt
- P54886
抗原
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