RAGE 抗体 (N-Term) (Biotin)
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Quick Overview for RAGE 抗体 (N-Term) (Biotin) (ABIN7967101)
抗原
See all RAGE (AGER) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-RAGE/AGER Antibody (monoclonal, 5C6C1) Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse,rat sequences by six amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human RAGE, different from the related mouse and rat sequences by six amino acids.
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亚型
- IgG2b
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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-237) antibody
AGER 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 180-402) antibodyAGER 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-404) antibodyAGER 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 151-250) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-274) antibodyAGER 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) antibodyAGER 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (N-Term) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 43-404) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (N-Term) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 小鼠 Monoclonal 5C6C1 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) antibody (Cy3)AGER 适用: 人, Cow WB, IHC, ELISA, ICC, IHC (p) 宿主: 小鼠 Monoclonal DD-A11 Cy3
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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别名
- AGER
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背景
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Background: The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. And RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment.
Gene Full Name: advanced glycosylation end-product specific receptor
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基因ID
- 177
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UniProt
- Q15109
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途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
抗原
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