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RAGE 抗体 (N-Term) (HRP)

The HRP-conjugated 兔 多克隆 anti-RAGE antibody (ABIN7967085) specifically detects RAGE in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7967085
发货至: 中国
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Quick Overview for RAGE 抗体 (N-Term) (HRP) (ABIN7967085)

抗原

See all RAGE (AGER) 抗体
RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

适用

  • 203
  • 152
  • 125
  • 7
  • 5
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  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 193
  • 23
  • 4
  • 3
  • 3
  • 2

克隆类型

  • 188
  • 39
  • 1
多克隆

标记

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This RAGE antibody is conjugated to HRP

应用范围

  • 144
  • 81
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  • 20
  • 14
  • 12
  • 11
  • 9
  • 3
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 39
    • 16
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    • 12
    • 9
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    • 7
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term

    原理

    Anti-RAGE/AGER Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by six amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human RAGE, different from the related mouse and rat sequences by six amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

    别名

    AGER

    背景

    Background: The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. And RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment.

    Gene Full Name: advanced glycosylation end-product specific receptor

    Sequence Similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

    基因ID

    177

    UniProt

    Q15109

    途径

    Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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