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beta 2 Adrenergic Receptor 抗体 (Middle Region)

The 兔 多克隆 anti-beta 2 Adrenergic Receptor antibody is suitable to detect beta 2 Adrenergic Receptor in samples from 人 和 大鼠. It has been validated for WB.
产品编号 ABIN7967012
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for beta 2 Adrenergic Receptor 抗体 (Middle Region) (ABIN7967012)

抗原

See all beta 2 Adrenergic Receptor (ADRB2) 抗体
beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

适用

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人, 大鼠

宿主

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克隆类型

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  • 2
多克隆

标记

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This beta 2 Adrenergic Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

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    Middle Region

    原理

    Anti-beta 2 Adrenergic Receptor/ADRB2 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse,rat sequences by three amino acids.

    产品特性

    Anti-beta 2 Adrenergic Receptor/ADRB2 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human ADRB2, different from the related mouse and rat sequences by three amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Rat, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

    别名

    ADRB2

    背景

    Background: ADRB2, also known as beta-2 adrenergic receptor, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs. It is mapped to 5q32. This receptor is ly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V)1.2. The genetic variation in the ADRB2 gene may be of major importance for obesity, energy expenditure, and lipolytic ADRB2 function in adipose tissue, at least in women. What’s more, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activity and beta-amyloid production, and the ADRB2 receptors activator may contribute to beta-amyloid accumulation in AD.

    Gene Full Name: adrenoceptor beta 2

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily.

    分子量

    47 kDa

    基因ID

    154

    UniProt

    P07550

    途径

    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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