ADAR 抗体 (AA 128-346) (Fluoro488)
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Quick Overview for ADAR 抗体 (AA 128-346) (Fluoro488) (ABIN7966674)
抗原
See all ADAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 128-346
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原理
- Anti-ADAR1 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human ADAR1 shares 90.2%,50.7% amino acid (aa) sequence identity with mouse,rat ADAR1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ADAR1 recombinant protein (Position: S128-Q346). Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
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别名
- ADAR
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背景
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Background: Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
Gene Full Name: adenosine deaminase RNA specific
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基因ID
- 103
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UniProt
- P55265
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途径
- Protein targeting to Nucleus
抗原
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