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ASXL1 抗体 (AA 14-1541) (Cy3)

The 兔 多克隆 anti-ASXL1 antibody is suitable to detect ASXL1 in samples from 人. It has been validated for FACS.
产品编号 ABIN7966574
发货至: 中国
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Quick Overview for ASXL1 抗体 (AA 14-1541) (Cy3) (ABIN7966574)

抗原

See all ASXL1 抗体
ASXL1 (Additional Sex Combs Like 1 (ASXL1))

适用

  • 53
  • 36
  • 12

宿主

  • 50
  • 6

克隆类型

  • 50
  • 6
多克隆

标记

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  • 2
  • 1
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This ASXL1 antibody is conjugated to Cy3

应用范围

  • 35
  • 31
  • 19
  • 15
  • 14
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Flow Cytometry (FACS)
  • 抗原表位

    • 14
    • 12
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    AA 14-1541

    原理

    Anti-ASXL1 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ASXL1 recombinant protein (Position: A14-R1541).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ASXL1 (Additional Sex Combs Like 1 (ASXL1))

    别名

    ASXL1

    背景

    Background: Putative Polycomb group protein ASXL1 is a protein that in humans is encoded by the ASXL1 gene. This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.

    Gene Full Name: ASXL transcriptional regulator 1

    基因ID

    171023

    UniProt

    Q8IXJ9

    途径

    Retinoic Acid Receptor Signaling Pathway
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