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AFT1 抗体 (AA 1-271) (FITC)

The FITC-conjugated 兔 多克隆 anti-AFT1 antibody (ABIN7965819) specifically detects AFT1 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7965819
发货至: 中国
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Quick Overview for AFT1 抗体 (AA 1-271) (FITC) (ABIN7965819)

抗原

See all AFT1 抗体
AFT1 (Activating Transcription Factor 1 (AFT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This AFT1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-271

    原理

    Anti-ATF1 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    AFT1 (Activating Transcription Factor 1 (AFT1))

    别名

    ATF1

    背景

    Background: ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.

    Gene Full Name: activating transcription factor 1

    Sequence Similarities: Belongs to the bZIP family. ATF subfamily.

    基因ID

    466

    UniProt

    P18846

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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