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AKAP12 抗体 (AA 387-1620) (Biotin)

The 兔 多克隆 anti-AKAP12 antibody is suitable to detect AKAP12 in samples from 小鼠 和 大鼠. It has been validated for IHC, WB 和 ELISA.
产品编号 ABIN7965275
发货至: 中国
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Quick Overview for AKAP12 抗体 (AA 387-1620) (Biotin) (ABIN7965275)

抗原

See all AKAP12 抗体
AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

适用

  • 21
  • 17
  • 17
  • 1
小鼠, 大鼠

宿主

  • 33
  • 2
  • 2
  • 1

克隆类型

  • 37
  • 1
多克隆

标记

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AKAP12 antibody is conjugated to Biotin

应用范围

  • 17
  • 13
  • 12
  • 12
  • 9
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 387-1620

    原理

    Anti-AKAP12 Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse AKAP12 recombinant protein (Position: E387-H1620).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

    别名

    Akap12

    背景

    Background: A-kinase anchor protein 12, aka AKAP250, is an enzyme that in humans is encoded by the AKAP12 gene. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinase A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

    Gene Full Name: A kinase anchor protein 12

    基因ID

    83397

    UniProt

    Q9WTQ5

    途径

    cAMP Metabolic Process
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