PFKFB4 抗体 (AA 1-298) (HRP)
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北京 101111
Quick Overview for PFKFB4 抗体 (AA 1-298) (HRP) (ABIN7965248)
抗原
See all PFKFB4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-298
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原理
- Anti-PFKFB4 Antibody HRP Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human PFKFB4 shares 97.3%,97% amino acid (aa) sequence identity with mouse,rat PFKFB4,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PFKFB4 recombinant protein (Position: M1-K298). Human PFKFB4 shares 97.3% and 97% amino acid (aa) sequence identity with mouse and rat PFKFB4, respectively.
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亚型
- IgG
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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) (AA 266-296) antibody
PFKFB4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB04059 unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) antibodyPFKFB4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) (AA 266-368) antibodyPFKFB4 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) (N-Term) antibodyPFKFB4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Cow, Pig, Bat, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) (N-Term) antibodyPFKFB4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) (AA 274-303) antibodyPFKFB4 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) antibodyPFKFB4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1C8 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- PFKFB4 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4))
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别名
- PFKFB4
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背景
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Background: 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 4 also known as PFKFB4 is an enzyme which in humans is encoded by the PFKFB4 gene. The protein encoded by this gene is one of four bifunctional kinase/phosphatases that regulate the concentration of the glycolytic byproduct fructose-2, 6-bisphosphate (F2, 6BP). The encoded protein is highly expressed in cancer cells and is induced by hypoxia. This protein is essential to the survival of cancer cells under conditions of hypoxia, because it increases the amount of F2, 6BP and ATP at a time when the cell cannot produce much of them. This finding suggests that this protein may be a good target for disruption in cancer cells, hopefully imperiling their survival. Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
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基因ID
- 5210
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UniProt
- Q16877
抗原
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