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XRN1 抗体 (AA 523-1198) (PE)

The 兔 多克隆 anti-XRN1 antibody is suitable to detect XRN1 in samples from 人 和 小鼠. It has been validated for FACS.
产品编号 ABIN7965140
发货至: 中国
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Quick Overview for XRN1 抗体 (AA 523-1198) (PE) (ABIN7965140)

抗原

See all XRN1 抗体
XRN1 (5'-3' Exoribonuclease 1 (XRN1))

适用

  • 33
  • 19
  • 3
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  • 1
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人, 小鼠

宿主

  • 32
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克隆类型

  • 32
  • 2
多克隆

标记

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This XRN1 antibody is conjugated to PE

应用范围

  • 20
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  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 11
    • 4
    • 2
    • 1
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    • 1
    • 1
    • 1
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    AA 523-1198

    原理

    Anti-XRN1 Antibody PE Conjugated

    预测反应

    Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human XRN1 recombinant protein (Position: K523-H1198). Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    XRN1 (5'-3' Exoribonuclease 1 (XRN1))

    别名

    XRN1

    背景

    Background: 5'-3' exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts ly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

    Gene Full Name: 5'-3' exoribonuclease 1

    基因ID

    54464

    UniProt

    Q8IZH2
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