XRN1 抗体 (AA 523-1198) (Fluoro594)
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北京 101111
Quick Overview for XRN1 抗体 (AA 523-1198) (Fluoro594) (ABIN7965136)
抗原
See all XRN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 523-1198
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原理
- Anti-XRN1 Antibody Fluoro594 Conjugated
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预测反应
- Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human XRN1 recombinant protein (Position: K523-H1198). Human XRN1 shares 93.2% amino acid (aa) sequence identity with mouse XRN1.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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别名
- XRN1
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背景
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Background: 5'-3' exoribonuclease 1 (Xrn1) is a protein that in humans is encoded by the XRN1 gene. This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts ly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.
Gene Full Name: 5'-3' exoribonuclease 1
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基因ID
- 54464
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UniProt
- Q8IZH2
抗原
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